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The upregulation of the tumour suppressor gene P53 leads to the accumulation of lipid hydroperoxides by inhibiting the expression of SLC7A11 and reducing the level of GSH, eventually triggering ferroptosis [81]
the delay allows these mechanisms to activate
2b and 3b), leading to the cellular production of taurine, pyruvate (Fig
[CrossRef] 85
2019;11:eaaw1565
6 Treatment remains challenging as commonly used medications in children, such as sulpiride and haloperidol, are limited in clinical application owing to adverse extrapyramidal side effects, alongside dizziness and somnolence
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